The COLON-FREE formula is not created for taste, but for effectiveness. Again, it’s the BITTERS that do the trick of flushing the liver and stimulating the digestive process. Take this anytime you want, with or without food. Start with a small teaspoonful or 5 to 6 capsules with water. If you need more power, increase amount until you get desired results.The Parasite formula already contains some colon herbs to help get rid of dead parasites and waste, so first see if you are going to the bathroom well enough with the parasite formula before taking the Colon formula. I prefer to take colon formula before bed.